Oxymetholone LA Pharma 100 tabs (50 mg/tab)
This drug is a steroid anabolic synthetic for the Administration oral. The athletes accepted duration of the course (on average up to 6 weeks), especially for fast and express a set of muscle mass and a corresponding increase in power.
The substance drug active (oxymetholone steroid) is a form modified of DHT (the form biologically active of the testosterone in the body human). Exhibits a strong anabolic (anabolic index - 320% of the endogenous testosterone) and moderate androgenic activity (index androgenic - 45% of the endogenous testosterone). It is considered one of the most potent oral anabolic steroids, the most urgent for the sports.
In this regard, recommended forcing experienced athletes advantageously. Similarly, women are not advisable, since even relatively small doses the risks of development virilization are stored. However, known that athletes, with experience in the use of Pharmacology, appealed to receive medicines oxymetholone, but only in oxymetholone reduced doses not exceeding 50 mg per day, to not cause the development of androgenic side effects.
Helps strengthen the anabolic processes about muscle. The main effect is expressed by a set of the mass muscle. Also, athletes are highly appreciated results improve athletic performance, increase endurance and performance, improve the function of joints and ligaments, eliminate the pain in the joints. In the reception is has produced the increase in the production of protein, the function of the reduction of the globulin, hormone sexual of the Union, the growth of the blood, stimulating the production of the hormone erythropoietin.
Oxymethalone is a 17 alpha-alkylated anabolic-androgenic steroid and a synthetic derivative of testosterone, whose anabolic effects are used to treat muscle wasting in HIV patients. The effects of testosterone in humans and other vertebrates occur by way of two main mechanisms: by activation of the androgen receptor (directly or as DHT), and by conversion to estradiol and activation of certain estrogen receptors. Free testosterone (T) is transported into the cytoplasm of target tissue cells, where it can bind to the androgen receptor, or can be reduced to 5α-dihydrotestosterone (DHT) by the cytoplasmic enzyme 5α-reductase. DHT binds to the same androgen receptor even more strongly than T, so that its androgenic potency is about 2.5 times that of T. The T-receptor or DHT-receptor complex undergoes a structural change that allows it to move into the cell nucleus and bind directly to specific nucleotide sequences of the chromosomal DNA. The areas of binding are called hormone response elements (HREs), and influence transcriptional activity of certain genes, producing the androgen effects.
Mechanism of action of oxymetholone:
Oxymetholone is an orally active synthetic anabolic steroid and a 17alpha-methylated derivative of dihydrotestosterone, with androgenic activity. Although oxymetholone has a low affinity for binding the androgen receptor (AR), it strongly activates AR-mediated signaling, which stimulates both protein synthesis and erythropoietin production. Free testosterone is transported into the cytoplasm of targeted tissue cells, where it can bind to the androgen receptors, or can be reduced to 5alpha-dihydrotestosterone by the cytoplasmic enzyme 5alpha-reductase.
Oxymetholone course and dose
Judging from the comments and the practices of the drug may result in muscle establish mass up to 10-15 kg of course. Due to the wide range of effects, is relevant not only in the bodybuilding but also almost any other sport, together with the high effort physical.
Is strong enough to be the only one in the course of taking steroids. However, the use combined of the Board takes to out more often with other steroids. Depending on the experience and the objectives of an athlete, in particular, can be effective with a lot of preparations of testosterone, stanozolol, or methenolone, as boldenone.
For them, athletes oxymetholone dose recommended, usually within 50-100 mg per day (dosage allowed to 100-200 mg by day if is tolerates). The frequency of reception-daily as a steroid not has a high duration of the action (up to 15 hours after the Administration).
Immediately after completing the course, compulsory post-cycle is therapy. PCT can involve the use of citrate of clomiphene or tamoxifen effectively. The duration of treatment and dose of posterior a la carte treatment (average three weeks flat 10 10-40-40 50-150 mg of tamoxifen or clomiphene per day).
Combined course (example) enanthate testosterone and boldenone to a marked increase in muscle mass experienced by athletes. The duration of the oxymetholone course can be of up to 10 weeks. Doses and golf course - in average 100 mg Oxymetholone per day (1 to 6 weeks), 500 mg of testosterone enanthate per week (from 1st to last week) and 600 mg boldenone per week (from 1st to last week). To avoid effects adverse in the course also need receive mesterolone and anastrozole, and the therapy post-cycle-tamoxifen.
Pros of the oxymetholone:
- This steroid is quite famous among the bodybuilder community all over the world.
- Oxymetholone believed to encourage increased testosterone levels in the athlete’s body.
- It also improves muscle mass and makes them bigger inside by improving the surface area of the muscles.
- By raising red blood cell production in the athlete’s body this can ensure the successful delivery of oxygen to your muscles that prevent muscle fatigue and energy loss from the body.
- It also improves muscle recovery by reducing the production of glucocorticoids from the body.
- It strengthens your workout by improving muscle power and allows you to enjoy the contest preparations.
- It is often added to the cutting cycle because of its ability to suppress appetite.
- Not only this allow you to eat in a calorie deficit, but it also allows you to keep your earned muscle.
- The amount of clean, dry muscle that you will gain depends on how you react to the drug.
- It is one of the safest anabolic drugs to use, provided that you are not predisposed to male pattern baldness and other androgenic side effects.
It is often described as an effective drug, although it is possible to know and controversial opinions. To judge by the statements positive, preparation of some big shows in reception to courses Masson aborn H, providing a demonstration of them results already in the first weeks. However, it is recommended to strictly comply with the dose, since otherwise the high probability of side effects of estrogen, progestin, or androgens characters.
Oxymetholone effects side
The possible effects side of the drug includes estrogen/progestin, androgens, and hepatotoxicity (toxicity moderate for the liver, that is a limitation of the dose consecutive more than 6-8 weeks in total). In particular, the abuse of them possible effects side such as the retention of water, the pressure blood high, the Gynecomastia, increase of the aggressiveness, the acne, fall of the hair, the Suppression of the testosterone, atrophy testicular, and several others.