Viagra 100 Pfizer 100mg
Buy cheap which can be is a drug for the treatment of erectile dysfunction, is a potent, selective inhibitor of phosphodiesterase-5. He was adopted shortly before the planned intercourse and has an effect only on natural mechanisms of occurrence of erection. The active ingredient Viagra 100 Pfizer 100mg buy cheap which can be is sildenafil citrate. This drug was developed in the late twentieth century.
But world popular drug Viagra 100 to buy at a low price which can be got due to side effects. The results of clinical studies of sildenafil conducted in 1992 with the participation of thousands of patients with coronary heart disease disappointing development of the drug Viagra, but it side effect reported by many study participants, namely a pronounced effect on the blood flow in the pelvic organs (including the penis), prompted the idea of using this drug for the treatment of erectile dysfunction. Later sildenafil citrate buys at a low price which have also shown effectiveness in treating pulmonary hypertension. In 1998, the drug was mentioned in connection with the award of the Nobel Prize in physiology and medicine.
Biochemical activity of the Viagra:
The active ingredient in the Viagra is sildenafil and most importantly this product is proved by the food drug and administration. If you want to take it orally then it is available as citrate salt of sildenafil.if we talk about the activity of sildenafil citrate then it is basically involved in the decrease in the activity of the cyclic guanosine monophosphate (cGMP)-specific monophosphatase type 5 (PDE5). If I discuss the physiologic mechanism then the working of that supplement involved the increased release of the nitric oxide in the corpus cavernosum. The nitric oxide is released during sexual stimulation. Sildenafil enhances the effects of the NO by inhibiting the enzyme phosphodiesterase type 5 (PDE5) into the corpus cavernosum. This enzyme is involved in the decrease in the NO number into this section of the penis.
The main purpose of using that supplement is to increase the no of cyclic guanosine monophosphate into the corpus cavernosum of the penis. For the increase of that supplement, it is necessary to inhibit the enzyme PDE5 as it is involved in the inhibition of the cyclic guanosine monophosphate production. And that drug is involved in the inhibition of the activity of the PDE5. When the PDE5 activity is inhibited then this inhibition leads to the increased production of the cyclic guanosine phosphate into the corpus cavernosal part of the male penis.
The Viagra course and Viagra dosage:
Using this drug correctly, according to established recommendations, a male can quite quickly get rid of the problem of erectile dysfunction and acting solely on natural mechanisms of occurrence of erection.
How to take sildenafil citrate buy cheap that can be, right? It's simple: usually, this drug to drink in about 1 hour before planned intercourse. Recommended dosage can vary. Single dose for adult men Viagra 100 Pfizer 100mg price we have low, is 50 mg 1 time per day, however, given the portability and efficiency it may be increased to 100 mg or on the contrary reduced to 25 milligrammes. The maximum single dose - 100 mg. Note that patients with impaired renal function mild or moderate severity, and also older men who plan reception sildenafil citrate buy cheap which can be, a correction of the dose up or down is not necessary. Those who are prone to severe kidney failure or liver damage, it is necessary to reduce the dosage to 25 mg a day. TCmax after ingestion on an empty stomach is 0.5-2 h, the bioavailability of 25-60%. In the case that the use of drugs sildenafil citrate price which we have available, was carried out together with fatty foods Cmax is reduced by 20-40% and is reached after an average of 1.5-3 hours. Total body clearance is 41 l / h, T1 / 2 - 3-5 hours.
Viagra side effects:
Note that the drug Viagra you may buy it from us can be not only a beneficial effect but some side. Among its potential side effects, there are such deviations as dizziness and headaches, flushing, nasal congestion. Also when you receive about yourself can give you indigestion or blurred vision (increased sensitivity to light, change the color of objects, the deterioration of visual acuity). Usually, the side effects of these drugs have mild or moderate severity and are temporary in nature.
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