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LEXAURIN - 30x - 3mg - Bromazepamum

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LEXAURIN - 30x - 3mg - Bromazepamum

Product: LEXAURIN
Manufacturer: KRKA
Quantity: 3 mg/tablet
Pack: 30 tablets

Steroid cycle: Antidepressants

Active substance: Bromazepamum

More details...

Promotion -8%

EUR 68.36

68,36 €

instead of 74,30 €

Availability : Available

2024
3524
Rated 5/5 based on 10 customer reviews

LEXAURIN - 30X - 3mg - BROMAZEPAMUM

The well-known drug that is widely used for indications such as attention syndrome, somatic complaints, and others.

Course

The total cycle time of treatment is not more than 8 weeks.
Pay attention, that the closer to the end of the course must gradually reduce the dose gradually. This will continue to avoid the most serious side effects.

The drug is best to take a few divided doses. This is not only convenient for the patient but also can improve reception performance.

In the case of a course of unforeseen side effects or worsening of the patient's general condition, you should consult a doctor immediately.

Dose

During outpatient, treatment dose should be about 1.5-3 mg 2-3 times a day.

In the event of the declaration of a patient in a medical institution of the hospital and the constant supervision of doctors, the dose may be increased to the level of 6-12 mg per day. In this case, as in the previous case, it is observed dosing regimen parts 2-3 times a day.

Side effects

It should not be named for monotherapy of depression, including anxious depression, due to the possibility of suicide. Paradoxical reactions are more common in children and elderly patients. In the case of paradoxical reactions, bromazepam should be abolished. It is recommended to reduce the dose gradually, as the risk of withdrawal symptoms above in a sharp rise of the drug.

Depending on risk increases when large doses and with increasing duration of reception, as well as in patients with alcohol dependence and drug history. Abolish bromazepam should be done gradually reducing the dose to reduce the risk of withdrawal symptoms.

In abrupt cancellation after long-term use or high doses, there is a withdrawal syndrome (a headache and muscle pain, agitation, anxiety, confusion, tremors, convulsions), in severe cases - depersonalization, hallucinations, convulsions (elimination sudden epilepsy). a transient syndrome where symptoms that lead to the appointment of bromazepam, resumed in a more pronounced way (bounce-Syndrome), also can be accompanied by mood changes, sleep disorders, anxiety and others.

Benzodiazepines can cause anterograde amnesia, that when the next dose using the upper limit of the therapeutic range is developed (bromazepam 6 mg per dose documented), in higher doses, increases your risk.

The drug is not recommended for people who are driving a vehicle, as well as people working in the production units and mechanisms capable of harming a person.

Pharmacology of that product:

Pharmacodynamics

There are a benzene ring and a pyridine ring into the molecular structure of that product. The benzene ring contains a nitrogen group into its molecular which comes in replacement of one carbon atom. Its molecular formula is named as 1, 4-benzodiazepine which means that the position of the nitrogen in the molecule is at 1 and 4th position.

Bromazepam is basically involved in the inhibition of the GABA related effects as it binds with the GABAA receptor of the GABA and causes the change in its conformation thus its activity also gets change. This product is long-acting and is metabolized via the oxidative pathways in the hepatocytes. This product does not have any type of antipsychotic or antidepressant quality. If the administration time of that product is night then it causes the reduction of the gastric juice release and production of rebound gastric juice to the next day is secreted.

This product is also involved in the alteration of the neuronal activities into the brain as it is involved in the alteration of the alpha and beta activities during the EEG recordings.

Pharmacokinetics

It is reported that this product gets metabolizes into the liver by the hepatic enzyme belong to the family of enzymes named cytochrome P450. After the metabolism of that product, the major metabolite is known as hydroxybromazepam which is highly active and is involved in the activities related to that product. The use of that product is highly reported for the treatment of somatic syndrome and attention syndrome and many other medical conditions.

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