Anastrozol 28 x 1 mg Sandoz
Anastrozole is a powerful anti-estrogen medication commonly sold under the brand name “Arimidex” and it is by that name most are familiar with the compound. As an anti-estrogen medication, Arimidex belongs to the aromatase inhibitor (AI) family and it is by this designation we truly see the function of this medication. First brought to the market by AstraZeneca, Arimidex was created in an effort to combat breast cancer in post-menopausal women. As we are aware estrogen is the enemy when it comes to breast cancer and Arimidex actively reduces the amount the body produces and it is by this trait one can already begin to see how this might be useful in-terms of anabolic steroid use. No, Arimidex is not an anabolic steroid; it is not a steroid in any shape or form but is commonly used in conjunction with anabolic steroids to combat estrogenic related side-effects.
Arimidex Cycles and Doses:
Most who supplement with Arimidex will be doing so for the prevention of side-effects while on cycle or to tighten up their physique for a physique based competition by reducing estrogen in the body. Most men will find 0.5mg every other day to be a good starting point while on cycle if it is needed for side-effect prevention with 1mg every other day generally being the most anyone will ever need for this purpose. However, if side-effects begin to manifest, particular Gynecomastia, many find supplementing with 1mg every day for a few weeks to be useful in combating this enemy; however, for this purpose, we would in most cases recommend the slightly stronger AI Letrozole but Arimidex will often suffice. If this occurs, simply supplement with 1mg every day until symptoms pass; once they do drop the dose to every other day and finish your intended cycle. It should be noted, this is not a 100% fail-safe plan; for some, no amount of any AI on earth will protect from Gynecomastia.
The same dosing can be applied in physique sports competition, most notably bodybuilding; it is very common for many bodybuilders to supplement with Arimidex for 12-16 weeks leading up to a competition at a dose of 1mg every other day. However, many bodybuilders will necessarily increase the dose to 1mg every day the final 10-14 days before the show in order to ensure they are as hard and water free as possible. However, we cannot recommend anyone supplement with this compound at that high of a dose for an extended period of time, as such dosing for extended periods would be too much estrogen suppression.
Women in the physique sports world also sometimes supplement with Arimidex to provide a dryer and harder look but this will generally only occur a few weeks out from a competition. Low doses for short periods of time can aid in a woman the same way it can a male competitor but as estrogen is slightly more important to a female use must necessarily be limited.
Pharmacology of the product
Pharmacodynamics
Anastrozole working is based on the inhibition of the conversion of the androgen to estrogen as this drug reversibly binds with that of the aromatase enzyme and blocks its activity. When the intake of the drug is 10mg per day then the inhibition of the aromatize enzyme which is recorded is 98.1% while when the intake is only 1mg then the inhibition of the aromatase is 96%-97.3%. however, we can say that the best results can be obtained by the use of 1mg of the anastrozole. The decreased aromatase enzyme activity leads to a decrease in estradiol level into the postmenopausal women upto85%. Stanozolol is ineffective for the corticosteroids and adrenal steroid levels into the body.
Pharmacokinetics
After the administration of the drug its bioavailability is not well known in humans however, its absorption into animals is observed and the results which are obtained are very well known. In humans, it is observed that the absorption line becomes linear over the dose 1-20mg and does not change even with frequent dosing. The type of food which is taken in with that product is not well known. In short, we can say that while using that product we can obtain better results while using lower doses. After the administration of the product, the maximum results are obtained in between 3 hours. If the administration of the drug is continuous then the best results could be obtained in only 3-4 hours. However, only 3-4 days are required for the suppression of the estradiol levels suppression into the body
The Side-Effects of Arimidex:
When it comes to side-effects it is always important to note all medications from every family carry with them a potential for side-effects; this includes everything to common cold medicine, pain killers, anabolic steroids and even AI’s such as Arimidex. However, when we examine Arimidex the potential for adverse side-effects appears to be very low. There do not appear to be any strong negative indirect side-effects due to supplemental use; however, use can lead to unwanted effects due to decreased estrogen in the body. In order for the human body to maintain a properly functioning endocrine system, we must have some estrogen present. Further, decreased estrogen can have a negative effect on cholesterol, a very side-effect problem you are trying to prevent through use; as you may have guessed when it comes to cholesterol there is a very fine line as it pertains to the estrogen hormone. However, Arimidex doesn’t appear to affect this greatly in a negative way and therefore remains a positive choice in this regard.
For the majority of steroid users, those who supplement with Arimidex will not want to do so indefinitely in the name of safety; while it is generally side-effect friendly it is not a good idea to keep estrogen levels so suppressed for far extended periods of time. Most will find such AI’s should only be used while on cycle and discontinued once the cycle is complete in order to let the body return to normal hormonal production. If side-effects are not a problem for you then perhaps no Arimidex will be needed; however, for competitive physique athletes, even if they rarely suffer from anabolic steroid side-effects Arimidex can still be very useful, as reduced estrogen will provide a leaner and harder physique. For this reason, many competitive bodybuilders supplement with Arimidex during their contest preparation
