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Finasteride Accord 30tabs x 5mg

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Finasteride Accord 30tabs x 5mg

PRODUCT: Finasteride Accord 5mg

MANUFACTURER: Accord

Quantity: 5mg/ml

Pack: 30 Tabs

Active SUBSTANCE: Finasteride

Steroid cycle: Anti Estrogens & PCT and also Weight loss

More details...

On sale -5%

EUR 62.48

62,48 €

instead of 65,77 €

Availability : Available

2024
3608
Rated 5/5 based on 13 customer reviews

Finasteride Accord 5mg

Finasteride that is a specific inhibitor of 5a-reductase. Harifin is the enzyme responsible for converting testosterone into DHT (dihydrotestosterone). Harifin can efficiently reduce the serum concentration of DHT, therefore Harifin minimizes the unwanted androgenic effects that result from its presence. Propecia is the same drug but the tablet contains only 115 of the Harifin dosage. Scientists have long believed that DHT was the main culprit in many cases of male hair loss (along with genetic factors), so there was little doubt after the release of Harifin that Finasteride would eventually be used for this purpose

Pharmacokinetics:

As it is present in the film-coated tablet form so its mode of administration is oral. The main oral bioavailability of it is approximately 65 percent. The absorption of finasteride is not affected by food or any meal. At steady – the state with 1 mg per day finasteride, the mean peak concentration of finasteride was 9.2 ng per ml ( 25 nmol per L), so the plasma concentration increased by 47 percent to 54 percent following 2.5 weeks of continued daily administration. The volume of distribution of finasteride is 76 L. its plasma protein binding is 90 percent. the drug has been found to cross the blood-brain in the barrier, whereas levels in semen were found to be undetectable.

Finasteride is extensively metabolized in the liver, first by hydroxylation via CYP3A4 and then by aldehyde dehydrogenase. It has many metabolites but there are two major metabolites, which are the tert – butyl side chain monohydroxylated and monocarboxylic acid metabolites. These metabolites show approximately 20 percent of the inhibitory activity of finasteride on 5 alpha-reductase. Hence, the metabolites of finasteride are not particularly active. Its concentration in the blood is at the maximum at a peak after taking its 4 hours. The drug has a terminal half-lifefe of 5 to 6hours in adult men (18 – 60 years of age ) and a terminal half-life of 8 hours or more in elderly men (more than 70 years of age ) it is eliminated as its metabolites 57% in the feces and 40% in the urine.

Dosage

There is no research to site on exactly what dosage would be the most appropriate for a steroid user. Logic woul dictate that the typically prescribed amount of Harifin / Propecia, a single 1mg tablet per day, would most likely be sufficient. In clinical trials the effect of just a single tablet is clearly dramatic.

Side effects

By minimizing the production of DHT, we should greatly reduce many of these harsh side effects and make our testosterone cycles more comfortable. In many instances, Harifin/Propecia can allow the athlete the use of steroid compounds (testosterone esters such as cypionate, enanthate, Sustanon etc.), Halotestin and methyltestosterone with much less androgenic side activity.

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