Methandrostenolone is a derivative of testosterone, modified so that the hormone's androgenic (masculinizing) properties are reduced and its anabolic (tissue building) properties preserved. Having a lower level of relative androgenicity than testosterone, methandrostenolone is classified as an "anabolic" steroid, although quite a distinct androgenic side is still present. This drug was designed, and is principally sold, as an oral medication, although it can also be found in a number of injectable veterinary solutions. Dianabol is today, and has historically been, the most commonly used oral anabolic/androgenic steroid for performance-enhancing purposes.
Mechanism of action:
It is also called methandrostenolone and is an androgen and anabolic steroid. It is used for the physique and performance enhancement. It binds to and activates the androgen receptor (AR) in order to exert its effects.it is metabolized by the 5a-reductase into methyl-1-testosterone. It is the substrate for aromatase and can be metabolized into estrogen methyl-estradiol. It is metabolized in the liver
Methandienone binds to and activates the androgen receptor (AR) in order to exert its effects. These include dramatic increases in protein synthesis, glycogenolysis, and muscle strength over a short space of time. It stimulates the anabolism and inhibits the catabolism.
- These compounds exhibit differential effects on muscle building (anabolic effects) and masculinity (androgenic effects).
- These drugs have positive effects on pharmacokinetics, androgen receptors activity, and metabolic pathways in the body.
- AAS compounds are often used in conjunction with each other. Anabolic effects are combined to enhance the anabolic effects.
- It enhances strength, power, muscle mass, and competition endurance. The drugs also account for aggressiveness in competitors on and off the field.
- It also stimulates the negative nitrogen balance by promoting the protein anabolism and stimulating the appetite in athletes after using it.
- Also, increase the serum protein values in the athlete’s body.
- This medication surprisingly increases the athlete's muscle strength.
17a-methyl-17b-hydroxy-l,4-androstadien-3-one l-Dehydro- 17a-methyltestosterone
Methandrostenolone is aromatized by the body, and is a moderately estrogenic steroid. Gynecomastia is often a concern during treatment, and may present itself quite early into a cycle (particularly when higher doses are used). At the same time water retention can become a problem, causing a notable loss of muscle definition as both subcutaneous water retention and fat levels build. Although classified as an anabolic steroid,androgenic side effects are still common with this substance. This may include bouts of oily skin, acne, and body/facial hair growth. Anabolic/androgenic steroids may also aggravate male pattern hair loss. C17alpha alkylated anabolic/androgenic steroids can be hepatotoxic. Prolonged or high exposure may result in liver damage. And the effects are not mild so you are recommended not to use this steroid if you are already suffering from liver disease. You may experience rapid body hair growth, severe acne, and hair loss. If you are genetically predisposed to male pattern baldness.
Studies have shown that taking an oral anabolic steroid with food may decrease its bioavailability. This is caused by the fat-soluble nature of steroid hormones, which can allow some of the drug to dissolve with undigested dietary fat, reducing its absorption from the gastrointestinal tract. For maximum utilization, oral forms of stanozolol should be taken on an empty stomach.
For physique or performance-enhancing purposes, the drug is also used intermittently, with cycles usually lasting between 6 and 8 weeks in length followed by 6-8 weeks off. Although a low dose of 5 mg daily may be effective for improving performance, athletes typically take much higher amounts. A daily dosage of 15-30 mg is most common, and typically produces very dramatic results.