Humulin R (REGULAR) Soluble human Insulin 100 IU/mL (HI 0210) Injection. Recombinant DNA origin (rDNA). 1 vial (U-100) 10 mL. * Contains m.cresol 0.25% added during manu
Brand/Manufacture
Eli Lilly
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Humulin R (REGULAR) Soluble human Insulin 100 IU/mL (HI 0210) Injection. Recombinant DNA origin (rDNA). 1 vial (U-100) 10 mL. * Contains m.cresol 0.25% added during manu
Brand/Manufacture
Eli Lilly
Humulin R U-100, when used subcutaneously, is usually given three or more times daily before meals. The dosage and timing of Humulin R U-100 should be individualized and determined, based on the physician's advice, in accordance with the needs of the patient. Humulin R U-100 may also be used in combination with oral antihyperglycemic agents or longer-acting insulin products to suit the needs of the individual patients with diabetes. The injection of Humulin R U-100 should be followed by a meal within approximately 30 minutes of administration.
Do not withdraw insulin from the pen using a syringe.
Mixing of Insulins
Humulin R U-100 should only be mixed as directed by the physician.
Humulin R U-100 is short-acting and is often used in combination with intermediate- or long-acting insulins.
The order of mixing and brand or model of syringe should be specified by the physician. A U-100 insulin syringe should always be used. Failure to use the correct syringe can lead to dosage errors.
In general, when an intermediate-acting insulin (e.g., NPH insulin isophane suspension) is mixed with short-acting soluble insulin (e.g., regular), the short-acting insulin should be drawn into the syringe first.
Storage
Not in-use (unopened): Humulin R U-100 vials not in-use should be stored in a refrigerator (2° to 8°C [36° to 46°F]), but not in the freezer.
In-use (opened): The Humulin R U-100 vial currently in-use can be kept unrefrigerated as long as it is kept as cool as possible [below 30°C (86°F)] away from heat and light. In-use vials must be used within 31 days or be discarded, even if they still contain Humulin R U-100.
Admixture: Infusion bags prepared with Humulin R U-100 as indicated under DOSAGE AND ADMINISTRATION are stable when stored in a refrigerator (2° to 8°C [36° to 46°F]) for 48 hours and then may be used at room temperature for up to an additional 48 hours.
Do not use Humulin R U-100 after the expiration date stamped on the label or if it has been frozen.