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PARLODEL 2.5 mg 30 tab / Bromocriptine

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PARLODEL 2.5 mg 30 tab / Bromocriptine

Product: PARLODEL 2.5 mg 30 tab / Bromocriptine

Manufacture: MEDA
Quantity: 2.5 mg/ml
Pack: 30tabs

Steroid cycle: Anti-Estrogens, PCT and also Weight loss

Active substance: Bromocriptine


Each tablet contains bromocriptine mesilate equivalent to 2.5 mg of bromocriptine base.

More details...

Promotion -5%

EUR 66.69

66,69 €

instead of 70,20 €

Availability : Available

2024
3675
Rated 5/5 based on 19 customer reviews

PARLODEL 2.5 mg 30 tab/Bromocriptine

Parlodel is the trade name for Bromocriptine mesylate (Bromo for short). It is an ergot derivative with D2 dopamine receptor agonist and D1 dopamine receptor antagonist activities. In medicine, it is a versatile drug with many uses thanks to its dopamine increasing effects. In bodybuilding, it’s used for its ability to inhibit prolactin, and during calorie restricted dieting.

History:

Bromocriptine was first used in the 1970′s for treatment of Parkinson’s, and to suppress HGH when high dosages were used. Since the late 80′s its been used off label for cocaine withdrawal; in addition, in 2009, it was approved by the FDA for treatment of type 2 diabetes for its effect at improving glycemic control. Many of its uses involve how bromo is related to dopamine increasing effects.

How it Works

Bromocriptine mesylate is a dopamine agonist. It activates dopamine receptors in the absence of that receptor’s physiological ligand, the neurotransmitter dopamine. Essentially, it will forcefully increase dopamine in the body.

Understanding Dopamine:

Dopamine is a hormone and neurotransmitter, which plays an important role in the human brain and body. With the brain, dopamine functions as a neurotransmitter: a chemical released by nerve cells to send signals to other nerve cells. When a person is addicted to drugs, dopamine levels will be increased.

Parkinson’s disease involves a dysfunction of the dopamine system, which will result in tremors and motion impairment. There is also evidence that schizophrenia involves altered levels of dopamine activity. Furthermore, ADHD and restless legs syndrome are believed to be associated with decreased dopamine activity.

Bodybuilding:

There are a couple ways Bromocriptine is used in bodybuilding.

Prolactin inhibition: Whenever a progestin based compound is used (trenbolone and nandrolone decanoate), prolactin levels will rise. Using bromocriptine to bring down prolactin levels will keep prolactin based gynecomastia away and also keep libido strong.

Calorie restricted dieting: When a bodybuilder cuts calories, leptin levels will drop and the body will respond by holding onto nutrient stores. It is believed that bromocriptine will help normalize the slowing metabolism during this time, and it will help maintain normal leptin stimulation. This phenomenon is connected to its dopamine effects.

Prolactin:

Prolactin is a hormone protein that plays the role of enabling females mammals to produce milk. It is not fully understood why males have prolactin, but we do know that it provides sexual gratification after ejaculation. After ejaculation, the male loses interest in sex, this is called the sexual refractory period, where prolactin levels go up. Therefore, lower prolactin levels should decrease the refractory period. In general, high prolactin levels can cause impotence and loss of interest in sex (low libido).

Uses and benefits:

Bromocriptine is used along with other medications ( such as levodopa) to treat specifically Parkinson’s disease. It can improve your ability to move and can decrease tremor or shakiness, slowed movement, stiffness, and unsteadiness. It may also decrease the number of episodes of not being able to move which is called “ on-off syndrome”

This drug is also used to treat high levels of a certain hormone made by the body or prolactin. High levels of prolactin may cause problems or issues such as unwanted breast milk, missed or stopped periods, difficulty becoming pregnant, decreased sperm production, and decreased sexual ability.

This drug may also be used to treat a type of tumor which causes high levels of prolactin or prolactin-secreting adenomas. It can help to reduce the size of the tumor. This drug is not recommended for stopping unwanted breast milk after pregnancy, abortion, or miscarriage because of possible serious side effects, such as high blood pressure, heart attack, stroke, seizure.

This drug is also used to treat high levels of growth hormone or acromegaly.

This drug is an ergot medication that works by acting like a certain natural substance or dopamine in the brain. It also prevents the release of certain hormones like growth hormone, prolactin. This drug can lower these hormone levels, but it does not cure the causes of the increased levels. This drug is not harmful, but the excess of everything is bad, so use this drug after the recommendation of the doctor with proper consultation. Otherwise, it is very dangerous to use.

 

Side Effects:

There is no shortage of possible side effects with Bromo, and many bodybuilders have avoided this drug for that reason.

Nausea is one of the most common side effects and is usually the first thing noticed. Guys will feel terrible when using bromocriptine, sick like they want to throw up. Low blood pressure, dizziness and confusion can also occur. There are a host of less likely sides including: anxiety, dry mouth, fatigue, headache, and lethargy.

Dosage:

The normal starting dose in bodybuilding is 2.5 to 5mg, either split during the day or everyday. If side effects become too great then cutting the dose in half can be effective.

Bromocriptine vs. Cabergoline vs. Pramipexole and Half Life

Bromo was very popular in the bodybuilding world until recently, and there are several reasons why it lost popularity. The side effects tend to be higher versus other dopamine drugs like cabergoline and pramipexole. Also, the half life is only 12 hours vs. cabergoline which has a 3-4 days half life. This means you must take it at least everyday, while cabergoline can be taken once every 3 days.

Trade Names:

Bromocriptine has several trade names.

Parlodel
Cycloset
Brotin (Pakistan)

 

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