Magma Elite Pharm methandienone 10mg / 200 tab
Methandienone(most powerful legal steroid) - a drug related to a series of anabolic steroids-left, he was gaining popularity as a drug used in sports medicine to increase muscle mass. The drug increases anabolic processes and inhibits catabolic processes caused by corticosteroids, helps increase muscle mass, it creates a positive nitrogen balance, accelerate the decomposition of body fat, suppresses the immune response by increasing synthesis inhibitor fraction C-1 of a compliment, and reducing P-2 P-4 fractions fulfilled, when taken regularly, actively developing secondary sexual characteristics of male type.
Methandienone course
Before the course starts receiving the drug should remember one important feature: the body can get used to receiving the steroid, and he can not bring the desired effect. Therefore, perhaps the most important rule is to gradually increase the dosage of the drug.
In addition, it is recommended to take the drug 6-9 and 18-21 hours. This is because at this time the blood level of testosterone is the male highest level.
Very often, the athletes taking the drug, separate 3, and in some cases, and 4 pieces per day. Such a technique may well be valid and will not do any harm to the body.
The initial phase of the course is approximately 3-4 weeks. As a rule, this course is used by beginners or athletes, who for some reason are not trained for a long time (eg due to injury).
This course also allows you to avoid the effect of habituation of the organism.
Since the drug increases appetite, it would be right to take the methane before a meal - this will allow you to use a larger amount of protein (which is, in principle, and need to know). The food that enters your body after ingestion of the drug, will serve as a source of energy and, above all, for the building blocks of muscle.
Chemistry:
This is a substrate for aromatase and it can be metabolized into the 17alpha methyl estradiol or estrogen methyl estradiol. Whereas the rate of aromatization is decreased relative to that for methyltestosterone or testosterone, the estrogen which is produced, is a metabolism resistant and therefore methandienone retains moderate or normal estrogenic activity.
It can cause side effects as well like gynecomastia as well as fluid retention. But the co-administration of an antiestrogen such as an aromatase inhibitor like anastrozole or a selective estrogen receptor modulator like we have tamoxifen can reduce or prevent such side effects of estrogen.
This methandienone has a progestogenic activity. It is subjected to extensive hepatic biotransformation by several enzymatic pathways.
- The primary or initial urinary metabolites are detectable for almost up to 3 days.
- And a recently discovered hydroxymethyl metabolite is present in the urine for up to 19 days after a single 5 mg oral dose.
- There are several metabolites that are unique to methandienone.
- There are different methods for detection in urine specimens usually involves gas mass-chromatography spectrometry.
Pharmacokinetics:
This methandienone has very high oral bioavailability and has a very low affinity for human serum sex hormone-binding globulin or SHBG, which is about 10% of that of testosterone and 2% of that of DHT. The product or drug is metabolized in the liver by 17-epimerization, 6 beta- hydroxylation, 3 alpha, and 3 beta-oxidation, 5 beta-reduction, and conjugation among other reactions. The elimination half-life of this drug or methandienone is about 3 hours or sometimes 6 hours. This is then excreted or eliminated in the urine.
Methandienone dose
The daily dose should be 20-25 mg. As already mentioned, allows distribution on the part of the reception. After the course, you are sure to make a post-cycle therapy and restore your liver.
In addition, athletes with experience to increase the dose, thus avoiding the undesirable effect of habituation. However, in this case, it should be noted that the drug is still quite powerful, and therefore increase your dose is slowly and in small quantities, while constantly keeping an eye on their own welfare and undergo a medical examination, as necessary.
Methandienone side effects
A significant excess of the standards set taking the drug, as well as potential health problems that the athlete can cause side effects.
According to doctors who examined athletes taking the drug, as well as athletes, most often side effects such as progression of atherosclerosis, peripheral edema, dyspeptic symptoms, dark urine, nausea, vomiting, general fatigue manifest, flatulence, insomnia.
Women can have a demonstration virilization (clitoral enlargement, deepening or hoarseness, disco and amenorrhea, hirsutism, steroid acne, oily skin), hypercalcemia (CNS depression, nausea, vomiting, fatigue). In addition, some men, depending on the physiological characteristics of the organism may occur in prepubertal - virilism (acne, penis enlargement, priapism, formation of secondary sexual characteristics), hyperpigmentation of idiopathic skin, slow or stop the growth (calcification areas epiphyseal growth of long bones); postpubertal - bladder irritation (increased urinary frequency urgency), mammalgia, gynaecomastia, priapism, reduced sexual function; elderly athletes - hyperplasia and / or prostate carcinoma.
In the case of overdose hepatotoxicity, it is possible. The treatment, in this case, is a gastric lavage, the appointment of symptomatic therapy.
